5PH Value Detection: Amniotic fluid is alkaline and the PH detection limit is 6.76.9. 4First Time Mothers: Our amniotic fluid test papers are specially prepared for first time mothers, so that expectant mothers will not be too worried about the condition of amniotic fluid. When you do not use it, the test paper will not be contaminated, which is very helpful to your health. 3Hygiene: Our PH test strips are individually sealed and packaged, which is clean and hygienic. ![]() ![]() 2High Sensitivity: When our amniotic fluid test pads related report diagnoses amniotic fluid leakage, the sensitivity reaches 97.6%, which can effectively detect whether the amniotic fluid is broken. The result is read visually by the presence of one or two lines in the test region of the strip.Feature 1Simple Operation: Our amniotic fluid test papers are very easy to operate, just stick it on the underwear like a normal pad, and tear it off after use. ![]() PAMG-1 is then detected in the sample through an amniotic fluid test strip (lateral flow device). A sample of cervicovaginal discharge (collected by vaginal swab) is placed into a vial with solvent for extraction. To minimize the frequency of false results, two monoclonal antibodies were selected to set the sensitivity threshold of the AmniSure ROM Test at the optimal low level of 5 ng/ ml.The maximum background concentration of PAMG-1 in cervicovaginal discharge is slightly lower than the sensitivity cut-off of the AmniSure ROM Test, reducing false results and allowing for ~99% accuracy (2). PAMG-1 was selected as a marker of fetal membranes rupture due to its high level in amniotic fluid, low level in blood, and extremely low background level in cervicovaginal discharge when fetal membranes are intact. The test employs highly sensitive monoclonal antibodies that detect even a minimal amount of PAMG-1, which is present in cervicovaginal discharge after rupture of fetal membranes. The AmniSure ROM Test uses the principles of immunochromatography to detect human PAMG-1 protein present in amniotic fluid. As an alternative to conventional methods of ROM detection, the AmniSure test has a 99% sensitivity and 98% specificity to support accuracy of negative and positive ROM clinical results. The AmniSure ROM Test is a rapid, non-invasive, amniotic fluid test that can aid in the detection of ROM, providing rapid, easy-to-interpret and timely results. Other available tests have limitations or are in some degree invasive (2). Accurate diagnosis of membranes rupture, however, remains a frequent clinical problem in obstetrics (2-4). Therefore the correct and timely diagnosis of ROM is of crucial importance for the clinician (2). Failure to identify patients with ROM can result in the failure to intervene appropriately.Ĭonversely, the false diagnosis of ROM can lead to inappropriate interventions (e.g., hospitalization or induction of labor). The AmniSure ROM Test kit is a self-contained system that can serve as part of your overall clinical evaluation of PROM, which is crucial to ensure appropriate obstetric measures are taken in the event of a rupture. All of these consequences significantly increase risk of fetal and maternal morbidity and mortality. Complications of pPROM include infectious morbidity in the mother and fetus, pulmonary hypoplasia of the fetus, prolapse of the umbilical cord, development of fetal deformities, and postnatal endometritis (2). pPROM accounts for 20% to 40% of PROM cases, and is associated with 20% to 50% of premature births. ![]() Risks of PROM at term are related to serious neonatal consequences such as pre-term delivery, fetal distress, prolapsed cord, abruptio placentae and infection (2). Management of patients with PROM and pPROM (pre-term PROM, occurring before 37 weeks gestation) is expensive and remains an important perinatal dilemma as the clinician attempts to balance the risk of prolonging gestation against the risks of infection (2). Premature rupture of fetal membranes (PROM) occurs in about 10% of pregnancies and poses one of the most important therapeutic dilemmas in current obstetric practice (2).
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